RGL3 antibody (Middle Region)

Catalog No. ABIN2774138

Product Details anti-RGL3 Antibody

Target: RGL3 (Ral Guanine Nucleotide Dissociation Stimulator-Like 3 (RGL3))

Binding Specificity: Middle Region

Reactivity: Human, Pig, Dog, Horse, Cow, Guinea Pig, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGL3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RNFSSLRAIL SALQSNPIYR LKRSWGAVSR EPLSTFRKLS QIFSDENNHL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RGL3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RGL3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 710 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGL3

Target: RGL3 (Ral Guanine Nucleotide Dissociation Stimulator-Like 3 (RGL3))

Alternative Name: RGL3 (RGL3 Products)

Synonyms: 1300003D20Rik antibody, mFLJ00153 antibody, ral guanine nucleotide dissociation stimulator-like 3 antibody, ral guanine nucleotide dissociation stimulator like 3 antibody, ral guanine nucleotide dissociation stimulator-like 3a antibody, Rgl3 antibody, RGL3 antibody, rgl3a antibody

Background: RGL3 is a guanine nucleotide exchange factor (GEF) for Ral-A. RGL3 is a potential effector of GTPase HRas and Ras-related protein M-Ras. RGL3 negatively regulates Elk-1-dependent gene induction downstream of HRas and MEKK1.
Alias Symbols: FLJ00153, FLJ32585, FLJ44275, MGC126805, MGC138163
Protein Interaction Partner: UBC,
Protein Size: 710

Molecular Weight: 78 kDa

Gene ID: 57139

NCBI Accession: NM_001035223, NP_001030300

UniProt: Q3MIN7