PNN antibody (Middle Region)

Catalog No. ABIN2774145

The Rabbit Polyclonal anti-PNN antibody has been validated for WB. It is suitable to detect PNN in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit and Horse.

Quick Overview for PNN antibody (Middle Region) (ABIN2774145)

Target: PNN (Pinin, Desmosome Associated Protein (PNN))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PNN Antibody

Binding Specificity: Middle Region

Sequence: RRSVDRKRRD TSGLERSHKS SKGGSSRDTK GSKDKNSRSD RKRSISESSR

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PNN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PNN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 717 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PNN

Target: PNN (Pinin, Desmosome Associated Protein (PNN))

Alternative Name: PNN

Background: PNN is the transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene, the core-binding sequence is 5'CAGGTG-3'. PNN is capable of reversing CTBP1-mediated transcription repression. Component of a splicing-dependent mul
Alias Symbols: DRS, SDK3, memA, pinin, DRSP
Protein Interaction Partner: SUMO3, UBC, CLK2, SRPK1, PRPF4B, SRPK2, HDAC11, CSNK2A2, CSNK2A1, RNPS1, EIF4A3, MAGOH, BARD1, GRK5, CDK2, HNRNPA1, Sap18, SIRT7, SF3A2, SUMO2, KIAA0101, RBM39, tat, SRRM2, SRRM1, TCEA2, ZCCHC17, PPIG, PNISR, SRSF4, CNGB1, YWHAG, DYNC1I2, PNN, CTBP2, CTBP
Protein Size: 717

Molecular Weight: 81 kDa

Gene ID: 5411

NCBI Accession: NM_002687, NP_002678

UniProt: Q9H307