PHYH antibody (N-Term)

Catalog No. ABIN2774157

This Rabbit Polyclonal antibody specifically detects PHYH in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Rabbit and Pig.

Quick Overview for PHYH antibody (N-Term) (ABIN2774157)

Target: PHYH (Phytanoyl-CoA 2-Hydroxylase (PHYH))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHYH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHYH Antibody

Binding Specificity: N-Term

Purpose: PHYH Antibody - N-terminal region

Sequence: TLPEILKYVE CFTGPNIMAM HTMLINKPPD SGKKTSRHPL HQDLHYFPFR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PHYH. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHYH

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56681-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHYH

Target: PHYH (Phytanoyl-CoA 2-Hydroxylase (PHYH))

Alternative Name: PHYH

Background:

Background Information: This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Name: Phytanoyl-CoA 2-hydroxylase

Alternative Symbols: RD, LN1, PAHX, LNAP1, PHYH1

Protein Name: Phytanoyl-CoA dioxygenase, peroxisomal

Molecular Weight: 39kDa

Gene ID: 5264

NCBI Accession: NP_001032626

UniProt: O14832

Pathways: Monocarboxylic Acid Catabolic Process