MEMO1 antibody (C-Term)

Catalog No. ABIN2774163

The Rabbit Polyclonal anti-MEMO1 antibody (ABIN2774163) specifically detects MEMO1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio) and Saccharomyces cerevisiae samples.

Quick Overview for MEMO1 antibody (C-Term) (ABIN2774163)

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEMO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MEMO1 Antibody

Binding Specificity: C-Term

Purpose: Memo1 Antibody - C-terminal region

Sequence: KLFSKYLADP SNLFVVSSDF CHWGQRFRYS YYDESQGEIY RSIEHLDKMG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Memo1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56787-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MEMO1

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Alternative Name: Memo1

Background:

Background Information: Memo1 may control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Memo1 is a mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.

Gene Name: Mediator of cell motility 1

Alternative Symbols: RGD1309929

Protein Name: Protein MEMO1

Molecular Weight: 32kDa

Gene ID: 298787

NCBI Accession: NP_001025088

UniProt: Q4QQR9