MEMO1 antibody (C-Term)

Catalog No. ABIN2774163

Product Details anti-MEMO1 Antibody

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEMO1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KLFSKYLADP SNLFVVSSDF CHWGQRFRYS YYDESQGEIY RSIEHLDKMG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Memo1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 297 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MEMO1

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Alternative Name: Memo1 (MEMO1 Products)

Synonyms: MGC89105 antibody, C2orf4 antibody, MEMO antibody, NS5ATP7 antibody, 0610016J10Rik antibody, D930048L02Rik antibody, RGD1309929 antibody, fi04d12 antibody, wu:fi04d12 antibody, zgc:55290 antibody, mediator of cell motility 1 antibody, mediator of cell motility 1 L homeolog antibody, MEMO1 antibody, memo1 antibody, Memo1 antibody, memo1.L antibody

Background: Memo1 may control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Memo1 is a mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
Alias Symbols: MGC116222, RGD1309929
Protein Size: 297

Molecular Weight: 32 kDa

Gene ID: 298787

NCBI Accession: NM_001029917, NP_001025088

UniProt: Q4QQR9