CNOT4 antibody (Middle Region)

Catalog No. ABIN2774204

This Rabbit Polyclonal antibody specifically detects CNOT4 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio) and Pig.

Quick Overview for CNOT4 antibody (Middle Region) (ABIN2774204)

Target: CNOT4 (CCR4-NOT Transcription Complex Subunit 4 (CNOT4))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CNOT4 Antibody

Binding Specificity: Middle Region

Sequence: AGIPASSGNS LDSLQDDNPP HWLKSLQALT EMDGPSAAPS QTHHSAPFST

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CNOT4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CNOT4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 639 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNOT4

Target: CNOT4 (CCR4-NOT Transcription Complex Subunit 4 (CNOT4))

Alternative Name: CNOT4

Background: CNOT4 has E3 ubiquitin ligase activity. The CCR4-NOT complex functions as general transcription regulation complex.
Alias Symbols: CLONE243, NOT4, NOT4H
Protein Interaction Partner: EP300, UBE2D1, UBC5, CNOT1, UBE2E3, UBE2E1, UBE2D2, UBC, CNOT4, ELAVL1, KDM5C, UBE2W, UBE2D4, UBE2N, UBE2D3, CNOT8, UBE2B, CDC39,
Protein Size: 639

Molecular Weight: 70 kDa

Gene ID: 4850

NCBI Accession: NM_013316, NP_037448

UniProt: O95628