IKZF2 antibody (Middle Region)

Catalog No. ABIN2774209

The Rabbit Polyclonal anti-IKZF2 antibody (ABIN2774209) specifically detects IKZF2 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit and Saccharomyces cerevisiae samples.

Quick Overview for IKZF2 antibody (Middle Region) (ABIN2774209)

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKZF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IKZF2 Antibody

Binding Specificity: Middle Region

Purpose: IKZF2 Antibody - middle region

Sequence: EREASPSNSC LDSTDSESSH DDHQSYQGHP ALNPKRKQSP AYMKEDVKAL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 82%

Characteristics: This is a rabbit polyclonal antibody against IKZF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IKZF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57975-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IKZF2

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Alternative Name: IKZF2

Background:

Background Information: IKZF2 is associates with Ikaros at centromeric heterochromatin.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Gene Name: IKAROS family zinc finger 2 (Helios)

Alternative Symbols: ANF1A2, HELIOS, ZNF1A2, ZNFN1A2

Protein Name: Zinc finger protein Helios

Molecular Weight: 59kDa

Gene ID: 22807

NCBI Accession: NP_057344

UniProt: Q9UKS7