EGR1 antibody (Middle Region)

Catalog No. ABIN2774222

This Rabbit Polyclonal antibody specifically detects EGR1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Sheep and Guinea Pig.

Quick Overview for EGR1 antibody (Middle Region) (ABIN2774222)

Target: EGR1 (Early Growth Response 1 (EGR1))

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EGR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EGR1 Antibody

Binding Specificity: Middle Region

Sequence: PSPVPTSFSS PGSSTYPSPV HSGFPSPSVA TTYSSVPPAF PAQVSSFPSS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against EGR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EGR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 543 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EGR1

Target: EGR1 (Early Growth Response 1 (EGR1))

Alternative Name: EGR1

Background: Early Growth Response Protein 1 (EGR1, Krox-24 protein, nerve growth factor-induced protein A, Transcription factor ETR103, Zinc finger protein 225) belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a tr
Alias Symbols: AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225
Protein Interaction Partner: CEBPB, WT1, SUMO1, TP53, MDM2, EP300, CDKN2A, SRA1, IL1B, PTEN, SP1, SNAI1, TBX2, PFDN5, SREBF2, ERBB3, NAB2, PITX1, NAB1, NFATC2, CREBBP, PSMA3, JUN, RELA, CSNK2A1, NFATC1, GADD45B, GADD45A,
Protein Size: 543

Molecular Weight: 57 kDa

Gene ID: 1958

NCBI Accession: NM_001964, NP_001955

UniProt: P18146

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity