GAN antibody (Middle Region)
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- Target See all GAN Antibodies
- GAN (Gigaxonin (GAN))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Mouse, Cow, Rabbit, Dog, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GAN antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IYLNDQNLCI PASSSFVYGA VPIGASIYVI GDLDTGTNYD YVREFKRSTG
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against GAN. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GAN
- Top Product
- Discover our top product GAN Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 597 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GAN (Gigaxonin (GAN))
- Alternative Name
- GAN (GAN Products)
- Synonyms
- MGC81691 antibody, GAN antibody, A330045G18 antibody, gigaxonin antibody, GAN1 antibody, KLHL16 antibody, gigaxonin L homeolog antibody, gigaxonin antibody, giant axonal neuropathy antibody, gan.L antibody, gan antibody, GAN antibody, Gan antibody
- Background
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This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN).
Alias Symbols: FLJ38059, GAN1, KLHL16
Protein Interaction Partner: RELA, HSP90AA1, CUL3, UBA1, TBCB, UBC, ATG16L1, RBX1, MAP1B, SFN,
Protein Size: 597 - Molecular Weight
- 66 kDa
- Gene ID
- 8139
- NCBI Accession
- NM_022041, NP_071324
- UniProt
- Q9H2C0
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