Caspase 6 antibody (Middle Region)
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- Target See all Caspase 6 (CASP6) Antibodies
- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caspase 6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QACRGNQHDV PVIPLDVVDN QTEKLDTNIT EVDAASVYTL PAGADFLMCY
- Predicted Reactivity
- Human: 100%, Mouse: 82%, Pig: 77%
- Characteristics
- This is a rabbit polyclonal antibody against CASP6. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CASP6
- Top Product
- Discover our top product CASP6 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 293 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
- Alternative Name
- CASP6 (CASP6 Products)
- Synonyms
- xCaspase-6 antibody, mch2 antibody, caspase-6 antibody, zgc:112960 antibody, CASP6 antibody, casp6 antibody, Mch2 antibody, mCASP-6 antibody, MCH2 antibody, caspase 6 L homeolog antibody, caspase 6 antibody, caspase 6, apoptosis-related cysteine peptidase antibody, group XIIA secretory phospholipase A2 antibody, caspase-6 antibody, casp6.L antibody, casp6 antibody, CASP6 antibody, CpipJ_CPIJ017008 antibody, Casp6 antibody
- Background
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This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
Alias Symbols: MCH2
Protein Interaction Partner: CASP6, XIAP, CRYAB, UBC, CASP3, RB1, IKBKG, PRKAB2, SP1, COPS6, SATB1, TAB1, MAPK6, PIN1, UBE4A, NUAK1, UBE4B, CHD3, PSME3, EIF2S1, CFLAR, PPL, NEDD4, SRP72, CASP8, CASP10, TRAF1, PSEN2, SRF, VIM, PRKCZ, MAPT, LMNB1, LMNA, KRT18, HTT, TOP1, DSP, PCYT1A, T
Protein Size: 293 - Molecular Weight
- 33 kDa
- Gene ID
- 839
- NCBI Accession
- NM_001226, NP_001217
- UniProt
- P55212
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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