USP47 antibody (Middle Region)

Catalog No. ABIN2774253

The Rabbit Polyclonal anti-USP47 antibody has been validated for WB. It is suitable to detect USP47 in samples from Human, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse and Rat.

Quick Overview for USP47 antibody (Middle Region) (ABIN2774253)

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Reactivity: Human, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP47 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-USP47 Antibody

Binding Specificity: Middle Region

Sequence: SITSSRRTKA NEGKKETWDT AEEDSGTDSE YDESGKSRGE MQYMYFKAEP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against USP47. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human USP47

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1287 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USP47

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Alternative Name: USP47

Background: USP47 is a putative ubiquitin-specific-processing protease that regulates cell growth and survival. USP47 probably regulates CDC25A expression at a transcriptional level. USP47 may be catalytically inactive although it seems to have kept all necessary active site residues.
Alias Symbols: DKFZp686C13257, FLJ20727, TRFP
Protein Interaction Partner: KIFC3, FBXW11, AP4M1, BTRC, UBC, WDR44, ATP6V1H, GMPPB, PDXDC1, KATNA1, HDAC6, SNCA, GRK5, SIRT7, PLA2G2A, MED9, MED29,
Protein Size: 1287

Molecular Weight: 147 kDa

Gene ID: 55031

NCBI Accession: NM_017944, NP_060414

UniProt: B3KXF5

Pathways: Negative Regulation of intrinsic apoptotic Signaling