Ubiquilin 2 antibody (N-Term)

Catalog No. ABIN2774254

The Rabbit Polyclonal anti-Ubiquilin 2 antibody has been validated for WB. It is suitable to detect Ubiquilin 2 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit and Guinea Pig.

Quick Overview for Ubiquilin 2 antibody (N-Term) (ABIN2774254)

Target: Ubiquilin 2 (UBQLN2)

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubiquilin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Ubiquilin 2 Antibody

Binding Specificity: N-Term

Sequence: LKDQDTLIQH GIHDGLTVHL VIKSQNRPQG QSTQPSNAAG TNTTSASTPR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 87%, Rabbit: 87%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against UBQLN2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBQLN2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 624 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Ubiquilin 2

Target: Ubiquilin 2 (UBQLN2)

Alternative Name: UBQLN2

Background: This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein.
Alias Symbols: CHAP1, DSK2, FLJ10167, FLJ56541, HRIHFB2157, N4BP4, PLIC2, ALS15
Protein Interaction Partner: UBC, SHFM1, PDE12, AARSD1, RNASEH2B, NPLOC4, WDR4, CUL5, VBP1, TPD52L2, RPA2, PRKACA, PFDN2, P4HB, MARCKS, DNAJB1, CALU, ADSL, FAF2, FBXO25, TARDBP, C1QA, PRPF40A, RNF11, CD93, UBL7, ZFYVE19, SSSCA1, SEC23A, YAP1, UBA2, USP34, ZRANB2, SNAP23, USP9X, STAM,
Protein Size: 624

Molecular Weight: 66 kDa

Gene ID: 29978

NCBI Accession: NM_013444, NP_038472

UniProt: Q9UHD9