Lcor antibody (C-Term)

Catalog No. ABIN2774271

This Rabbit Polyclonal antibody specifically detects Lcor in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Lcor antibody (C-Term) (ABIN2774271)

Target: Lcor (Ligand Dependent Nuclear Receptor Corepressor (Lcor))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lcor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Lcor Antibody

Binding Specificity: C-Term

Sequence: EGDPGSKQPR KKRGRYRQYN SEILEEAISV VMSGKMSVSK AQSIYGIPHS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against LCOR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LCOR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 433 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Lcor

Target: Lcor (Ligand Dependent Nuclear Receptor Corepressor (Lcor))

Alternative Name: LCOR

Background: LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).
Alias Symbols: FLJ38026, KIAA1795, MLR2, RP11-175O19.1
Protein Interaction Partner: TRAF1, GOLGA2, CTBP2, CTBP1, AR, KLF6, HDAC6, HDAC4, VDR, HDAC1, ESR1, HDAC3,
Protein Size: 433

Molecular Weight: 47 kDa

Gene ID: 84458

NCBI Accession: NM_032440, NP_115816

UniProt: Q96JN0