NHEJ1 antibody (C-Term)

Catalog No. ABIN2774319

This anti-NHEJ1 antibody is a Rabbit Polyclonal antibody detecting NHEJ1 in WB. Suitable for Human, Rat and Dog.

Quick Overview for NHEJ1 antibody (C-Term) (ABIN2774319)

Target: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Reactivity: Human, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NHEJ1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NHEJ1 Antibody

Binding Specificity: C-Term

Sequence: IDSQCVNQPE QLVSSAPTLS APEKESTGTS GPLQRPQLSK VKRKKPRGLF

Predicted Reactivity: Dog: 93%, Human: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against NHEJ1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 299 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NHEJ1

Target: NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))

Alternative Name: NHEJ1

Background: Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
Alias Symbols: FLJ12610, XLF
Protein Interaction Partner: UBC, NAA20, XRCC4, NHEJ1, LIG4,
Protein Size: 299

Molecular Weight: 33 kDa

Gene ID: 79840

NCBI Accession: NM_024782, NP_079058

UniProt: Q9H9Q4

Pathways: DNA Damage Repair