CFHR1 antibody (N-Term)

Catalog No. ABIN2774339

The Rabbit Polyclonal anti-CFHR1 antibody has been validated for WB. It is suitable to detect CFHR1 in samples from Human and Rat.

Quick Overview for CFHR1 antibody (N-Term) (ABIN2774339)

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CFHR1 Antibody

Binding Specificity: N-Term

Sequence: NHGILYDEEK YKPFSQVPTG EVFYYSCEYN FVSPSKSFWT RITCTEEGWS

Predicted Reactivity: Human: 100%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against CFHR1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 330 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CFHR1

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Alternative Name: CFHR1

Background: This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
Alias Symbols: CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2, MGC104329
Protein Interaction Partner: PRDX4, LBP, APOA1, CFH,
Protein Size: 330

Molecular Weight: 36 kDa

Gene ID: 3078

NCBI Accession: NM_002113, NP_002104

UniProt: Q03591