MRPS18B antibody (N-Term)

Catalog No. ABIN2774354

Product Details anti-MRPS18B Antibody

Target: MRPS18B (Mitochondrial Ribosomal Protein S18B (MRPS18B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS18B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SVPISPYKDE PWKYLESEEY QERYGSRPVW ADYRRNHKGG VPPQRTRKTC

Predicted Reactivity: Cow: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against MRPS18B. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 258 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPS18B

Target: MRPS18B (Mitochondrial Ribosomal Protein S18B (MRPS18B))

Alternative Name: MRPS18B (MRPS18B Products)

Synonyms: Ptd017 antibody, C6orf14 antibody, HSPC183 antibody, HumanS18a antibody, MRP-S18-2 antibody, MRPS18-2 antibody, PTD017 antibody, S18amt antibody, 2400002C15Rik antibody, mitochondrial ribosomal protein S18B antibody, Mrps18b antibody, MRPS18B antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins.
Alias Symbols: C6orf14, DKFZp564H0223, HSPC183, HumanS18a, MRP-S18-2, MRPS18-2, PTD017, S18amt
Protein Interaction Partner: TUBGCP4, CEP250, TUBGCP3, VCP, TP53, NEDD1, UBC, PARK2, EXOSC6, EWSR1, mug82, ICT1, EBNA3B, RB1, MRPS9, MRPS26, MRPS25, MRPS35, MRPS22, UBR5, MRPS28, QARS, MYH9, KARS, HNRNPAB, FUS, CAND1, CUL3, Ybx1, NFKBIL1,
Protein Size: 258

Molecular Weight: 28 kDa

Gene ID: 28973

NCBI Accession: NM_014046, NP_054765

UniProt: Q9Y676