PRPF18 antibody (Middle Region)

Catalog No. ABIN2774355

The Rabbit Polyclonal anti-PRPF18 antibody (ABIN2774355) specifically detects PRPF18 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for PRPF18 antibody (Middle Region) (ABIN2774355)

Target: PRPF18 (PRP18 Pre-mRNA Processing Factor 18 (PRPF18))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRPF18 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRPF18 Antibody

Binding Specificity: Middle Region

Purpose: PRPF18 Antibody - middle region

Sequence: NKGLRNDLKA ALDKIDQQYL NEIVGGQEPG EEDTQNDLKV HEENTTIEEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PRPF18. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PRPF18

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62903-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRPF18

Target: PRPF18 (PRP18 Pre-mRNA Processing Factor 18 (PRPF18))

Alternative Name: PRPF18

Background:

Background Information: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18.

Gene Name: protein phosphatase 1, regulatory subunit 3C

Alternative Symbols: PRP18, hPrp18

Protein Name: Pre-mRNA-splicing factor 18

Molecular Weight: 40kDa

Gene ID: 8559

NCBI Accession: NP_003666

UniProt: Q99633