RHD antibody (N-Term)

Catalog No. ABIN2774362

The Rabbit Polyclonal anti-RHD antibody is suitable to detect RHD in samples from Human. It has been validated for WB.

Quick Overview for RHD antibody (N-Term) (ABIN2774362)

Target: RHD (Rh Blood Group, D Antigen (RHD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RHD Antibody

Binding Specificity: N-Term

Purpose: RHD Antibody - N-terminal region

Sequence: WALTLEAALI LLFYFFTHYD ASLEDQKGLV ASYQVGQDLT VMAAIGLGFL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against RHD. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63086-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RHD

Target: RHD (Rh Blood Group, D Antigen (RHD))

Alternative Name: RHD

Background:

Background Information: The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Rh blood group, D antigen

Alternative Symbols: RH, Rh4, RH30, RhII, RhPI, DIIIc, RHCED, RHDel, RHPII, RhDCw, CD240D, RHXIII, RHDVA(TT), RhK562-II

Protein Name: RHD protein EMBL AAI39923.1

Molecular Weight: 35kDa

Gene ID: 6007

NCBI Accession: NP_001121163

UniProt: Q5XLT3