DACT1 antibody (Middle Region)

Catalog No. ABIN2774363

The Rabbit Polyclonal anti-DACT1 antibody is suitable to detect DACT1 in samples from Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Cow, Dog and Pig. It has been validated for WB.

Quick Overview for DACT1 antibody (Middle Region) (ABIN2774363)

Target: DACT1 (Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DACT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DACT1 Antibody

Binding Specificity: Middle Region

Sequence: LSLVQKKTHP VRTNKPRTSV NADPTKGLLR NGSVCVRAPG GVSQGNSVNL

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against DACT1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 836 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DACT1

Target: DACT1 (Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1))

Alternative Name: DACT1

Background: DACT1 positively regulates DVL2-mediated signaling pathways during development. It binds to DVL2 and impedes the degradation of CTNNB1/beta-catenin, thereby enhancing the transcriptional activation of target genes of the Wnt signaling pathway.
Alias Symbols: DAPPER, DAPPER1, DPR1, FRODO, HDPR1, THYEX3
Protein Interaction Partner: BECN1, PIK3C3, ATG14, CBX6, PPP1CC, Dact1, Dact3, C7orf25, TK1, SH3GL2, CSNK2B, LEF1, HDAC1,
Protein Size: 836

Molecular Weight: 92 kDa

Gene ID: 51339

NCBI Accession: NM_016651, NP_057735

UniProt: Q9NYF0

Pathways: Positive Regulation of fat Cell Differentiation