RGR antibody (N-Term)

Catalog No. ABIN2774370

The Rabbit Polyclonal anti-RGR antibody is suitable to detect RGR in samples from Human, Mouse, Rat, Horse, Pig, Rabbit, Cow, Dog and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for RGR antibody (N-Term) (ABIN2774370)

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Reactivity: Human, Mouse, Rat, Horse, Pig, Rabbit, Cow, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGR Antibody

Binding Specificity: N-Term

Purpose: RGR Antibody - N-terminal region

Sequence: SLLRVSHRRW PYGSDGCQAH GFQGFVTALA SICSSAAIAW GRYHHYCTRS

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 100%, Rat: 86%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RGR. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63387-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGR

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Alternative Name: RGR

Background:

Background Information: This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively).

Gene Name: Retinal G protein coupled receptor

Alternative Symbols: RP44

Protein Name: RPE-retinal G protein-coupled receptor

Molecular Weight: 32kDa

Gene ID: 5995

NCBI Accession: NP_002912

UniProt: P47804