Exonuclease 1 antibody (C-Term)

Catalog No. ABIN2774373

The Rabbit Polyclonal anti-Exonuclease 1 antibody has been validated for WB. It is suitable to detect Exonuclease 1 in samples from Human, Mouse, Rat, Guinea Pig, Rabbit, Cow and Dog.

Quick Overview for Exonuclease 1 antibody (C-Term) (ABIN2774373)

Target: Exonuclease 1 (EXO1)

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Exonuclease 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Exonuclease 1 Antibody

Binding Specificity: C-Term

Sequence: TTKIKPLGPA RASGLSKKPA SIQKRKHHNA ENKPGLQIKL NELWKNFGFK

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 77%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EXO1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 803 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Exonuclease 1

Target: Exonuclease 1 (EXO1)

Alternative Name: EXO1

Background: This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
Alias Symbols: HEX1, hExoI
Protein Interaction Partner: YWHAB, MLH1, PCNA, UBC, SUMO2, YWHAQ, YWHAZ, YWHAH, YWHAG, YWHAE, MSH2, KPNA4, KPNB1, SFN, ATM, PMS2, PMS1, BLM, MSH3,
Protein Size: 803

Molecular Weight: 89 kDa

Gene ID: 9156

NCBI Accession: NM_003686, NP_003677

UniProt: E7EVV0

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response