PDIA3 antibody (C-Term)

Catalog No. ABIN2774375

The Rabbit Polyclonal anti-PDIA3 antibody has been validated for WB, IHC and IP. It is suitable to detect PDIA3 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Cow, Rabbit, Horse, Goat, Sheep and Zebrafish (Danio rerio).

Quick Overview for PDIA3 antibody (C-Term) (ABIN2774375)

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Rabbit, Horse, Goat, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDIA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-PDIA3 Antibody

Binding Specificity: C-Term

Sequence: YFSPANKKLN PKKYEGGREL SDFISYLQRE ATNPPVIQEE KPKKKKKAQE

Predicted Reactivity: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PDIA3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 505 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDIA3

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Alternative Name: PDIA3

Background: This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Alias Symbols: ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC
Protein Interaction Partner: FUS, UBC, MDM2, SUZ12, ABCE1, RBBP4, RAB1A, PGD, MTAP, MTPN, BCCIP, CNDP2, NANS, DAK, ACOT7, NPEPPS, SLC9A3R1, RPL23, SMS, LDHA, HSPD1, CSE1L, ATP6V1A, ADSS, EGFR, UBD, CANX, CALR, HDAC10, MTOR, EFEMP1, ATF2, COL6A1, CLU, APP, ADAM10, AGRN, DCBLD1, RICTOR
Protein Size: 505

Molecular Weight: 56 kDa

Gene ID: 2923

NCBI Accession: NM_005313, NP_005304

UniProt: P30101

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis