PMM2 antibody (Middle Region)

Catalog No. ABIN2774385

The Rabbit Polyclonal anti-PMM2 antibody is suitable to detect PMM2 in samples from Human, Mouse, Rat, Rabbit, Guinea Pig, Dog, Horse, Cow and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for PMM2 antibody (Middle Region) (ABIN2774385)

Target: PMM2 (Phosphomannomutase 2 (PMM2))

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Dog, Horse, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PMM2 Antibody

Binding Specificity: Middle Region

Purpose: PMM2 Antibody - middle region

Sequence: IEFRNGMLNV SPIGRSCSQE ERIEFYELDK KENIRQKFVA DLRKEFAGKG

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against PMM2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63938-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PMM2

Target: PMM2 (Phosphomannomutase 2 (PMM2))

Alternative Name: PMM2

Background:

Background Information: The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.

Gene Name: Phosphomannomutase 2

Alternative Symbols: PMI, CDG1, CDGS, PMI1, CDG1a, PMM 2

Protein Name: Phosphomannomutase 2

Molecular Weight: 28kDa

Gene ID: 5373

NCBI Accession: NP_000294

UniProt: O15305