ITIH5 antibody (N-Term)

Catalog No. ABIN2774449

The Rabbit Polyclonal anti-ITIH5 antibody (ABIN2774449) specifically detects ITIH5 in WB. The antibody is reactive with Human, Cow, Dog, Rabbit, Horse and Pig samples.

Quick Overview for ITIH5 antibody (N-Term) (ABIN2774449)

Target: ITIH5 (Inter alpha Globulin Inhibitor H5 (ITIH5))

Reactivity: Human, Cow, Dog, Rabbit, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITIH5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ITIH5 Antibody

Binding Specificity: N-Term

Purpose: ITIH5 Antibody - N-terminal region

Sequence: AAFITNFTML IGDKVYQGEI TEREKKSGDR VKEKRNKTTE ENGEKGTEIF

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 86%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against ITIH5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ITIH5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66381-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ITIH5

Target: ITIH5 (Inter alpha Globulin Inhibitor H5 (ITIH5))

Alternative Name: ITIH5

Background:

Background Information: This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants.

Alternative Symbols: ITI-HC5, PP14776

Protein Name: Inter-alpha-trypsin inhibitor heavy chain H5

Molecular Weight: 103kDa

Gene ID: 80760

NCBI Accession: NP_085046

UniProt: Q86UX2

Pathways: Glycosaminoglycan Metabolic Process