ATP6V0D1 antibody (C-Term)

Catalog No. ABIN2774453

The Rabbit Polyclonal anti-ATP6V0D1 antibody (ABIN2774453) specifically detects ATP6V0D1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Dog, Horse and Saccharomyces cerevisiae samples.

Quick Overview for ATP6V0D1 antibody (C-Term) (ABIN2774453)

Target: ATP6V0D1 (ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D1 (ATP6V0D1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Dog, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V0D1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATP6V0D1 Antibody

Binding Specificity: C-Term

Sequence: GGTTADAMCP ILEFEADRRA FIITINSFGT ELSKEDRAKL FPHCGRLYPE

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ATP6V0D1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ATP6V0D1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 351 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP6V0D1

Target: ATP6V0D1 (ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D1 (ATP6V0D1))

Alternative Name: ATP6V0D1

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously.
Alias Symbols: ATP6D, ATP6DV, FLJ43534, P39, VATX, VMA6, VPATPD
Protein Interaction Partner: UBC, STAU1, RPA3, RPA2, RPA1, LIG4, ERC1, ATP6V1B1, ATXN1,
Protein Size: 351

Molecular Weight: 39 kDa

Gene ID: 9114

NCBI Accession: NM_004691, NP_004682

UniProt: P61421

Pathways: Transition Metal Ion Homeostasis, Proton Transport, ER-Nucleus Signaling, Unfolded Protein Response