SPSB1 antibody (Middle Region)

Catalog No. ABIN2774457

The Rabbit Polyclonal anti-SPSB1 antibody is suitable to detect SPSB1 in samples from Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for SPSB1 antibody (Middle Region) (ABIN2774457)

Target: SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPSB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPSB1 Antibody

Binding Specificity: Middle Region

Sequence: RGLHVWQITW AMRQRGTHAV VGVATADAPL HSVGYTTLVG NNHESWGWDL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against SPSB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SPSB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 273 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPSB1

Target: SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))

Alternative Name: SPSB1

Background: SPSB1 is a probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Alias Symbols: SSB-1, SSB1
Protein Interaction Partner: PRMT6, KDM1A, SUV39H1, PRMT1, NOS2, HSP90AA1, ATM, TCEB2, TCEB1, RNF7, CUL5, Pawr, Ddx4, RASA1, MET, ELAVL1, UBC, TP73, TP53,
Protein Size: 273

Molecular Weight: 30 kDa

Gene ID: 80176

NCBI Accession: NM_025106, NP_079382

UniProt: Q96BD6