H2bfm antibody (Middle Region)

Catalog No. ABIN2774481

The Rabbit Polyclonal anti-H2bfm antibody is suitable to detect H2bfm in samples from Human. It has been validated for WB.

Quick Overview for H2bfm antibody (Middle Region) (ABIN2774481)

Target: H2bfm (H2BFM) (H2B Histone Family, Member M (H2BFM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2bfm antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-H2bfm Antibody

Binding Specificity: Middle Region

Purpose: H2BFM Antibody - middle region

Sequence: SCYLMAAASA MAEASSETTS E
EGQSIQEPKE ANSTKAQKQK RRGCRGSR

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against H2BFM. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human H2BFM

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67548-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for H2bfm

Target: H2bfm (H2BFM) (H2B Histone Family, Member M (H2BFM))

Alternative Name: H2BFM

Background:

Background Information: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the H2B histone family.

Gene Name: H2B histone family member M

Alternative Symbols: H2BM, H2BFM

Protein Name: histone H2B type F-M

Molecular Weight: 28kDa

Gene ID: 286436

NCBI Accession: NP_001157888

UniProt: P0C1H6