NSUN5 antibody (C-Term)

Catalog No. ABIN2774485

This Rabbit Polyclonal antibody specifically detects NSUN5 in WB. It exhibits reactivity toward Human.

Quick Overview for NSUN5 antibody (C-Term) (ABIN2774485)

Target: NSUN5 (NOP2/Sun Domain Family, Member 5 (NSUN5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSUN5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NSUN5 Antibody

Binding Specificity: C-Term

Sequence: ASPETTLSSG FFVAVIERVE VPSSASQAKA SAPERTPSPA PKRKKRQQRA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against NSUN5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NSUN5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 466 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NSUN5

Target: NSUN5 (NOP2/Sun Domain Family, Member 5 (NSUN5))

Alternative Name: NSUN5

Background: This gene encodes a member of the evolutionarily conserved NOL1/NOP2/Sun domain family. The encoded protein may function as a DNA methyltransferase in the nucleus. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: FLJ10267, MGC986, NOL1, NOL1R, NSUN5A, WBSCR20, WBSCR20A, p120
Protein Interaction Partner: SUMO1, UBC, NEDD8, CDK13, UBD,
Protein Size: 466

Molecular Weight: 50 kDa

Gene ID: 55695

NCBI Accession: NM_148956, NP_683759