NSUN5 antibody (AA 320-400)

Catalog No. ABIN7230144

This Rabbit Polyclonal antibody specifically detects NSUN5 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for NSUN5 antibody (AA 320-400) (ABIN7230144)

Target: NSUN5 (NOP2/Sun Domain Family, Member 5 (NSUN5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSUN5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NSUN5 Antibody

Binding Specificity: AA 320-400

Purpose: Rabbit Anti-NSUN5 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NSUN5 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NSUN5 protein at AA range: 320-400

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NSUN5

Target: NSUN5 (NOP2/Sun Domain Family, Member 5 (NSUN5))

Alternative Name: NSUN5

Background: Probable 28S rRNA (cytosine-C(5))-methyltransferase, NOL1-related protein, NOL1R, NOL1/NOP2/Sun domain family member 5, Williams-Beuren syndrome chromosomal region 20A proteinNSUN5 (NOP2/Sun RNA Methyltransferase Family Member 5) encodes a member of an evolutionarily conserved family of proteins that may function as methyltransferases. NSUN5 is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. There are two pseudogenes for NSUN5 located in the same region of chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 47kD

Gene ID: 55695

UniProt: Q96P11