TTLL11 antibody (N-Term)

Catalog No. ABIN2774490

This Rabbit Polyclonal antibody specifically detects TTLL11 in WB. It exhibits reactivity toward Human and Rabbit.

Quick Overview for TTLL11 antibody (N-Term) (ABIN2774490)

Target: TTLL11 (Tubulin Tyrosine Ligase-Like Family, Member 11 (TTLL11))

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTLL11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TTLL11 Antibody

Binding Specificity: N-Term

Purpose: TTLL11 Antibody - N-terminal region

Sequence: QVLQRPPPTL PPSKPKPVQG LCPHGKPRDK GRSCKRSSGH GSGENGSQRP

Predicted Reactivity: Human: 100%, Rabbit: 92%

Characteristics: This is a rabbit polyclonal antibody against TTLL11. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TTLL11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67890-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TTLL11

Target: TTLL11 (Tubulin Tyrosine Ligase-Like Family, Member 11 (TTLL11))

Alternative Name: TTLL11

Background:

Background Information: TTLL11 is a polyglutamase which preferentially modifies alpha-tubulin. It is involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. TTLL11 is required for CCSAP localization to both spindle and cilia microtubules.

Alternative Symbols: C9orf20, C9orf148, TTLL11-IT1, bA244O19.1

Molecular Weight: 26kDa

Gene ID: 158135

NCBI Accession: NP_919228

UniProt: Q8NHH1