GON7 Subunit Of KEOPS Complex (GON7) (C-Term) antibody

Catalog No. ABIN2774521

There is 1 publication for this product available. The Rabbit Polyclonal anti-GON7 Subunit Of KEOPS Complex antibody is suitable to detect GON7 Subunit Of KEOPS Complex in samples from Human, Mouse, Cow, Dog, Horse, Pig and Rat. It has been validated for WB.

Quick Overview for GON7 Subunit Of KEOPS Complex (GON7) (C-Term) antibody (ABIN2774521)

Target: GON7 Subunit Of KEOPS Complex (GON7)

Reactivity: Human, Mouse, Cow, Dog, Horse, Pig, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Purpose: GON7 Antibody - C-terminal region

Sequence: LVQGEVQHRV AAAPDEDLDG DDEDDAEDEN NIDNRTNFDG PSAKRPKTPS

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 79%, Rat: 91%

Characteristics: This is a rabbit polyclonal antibody against C14orf142. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human C14orf142

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP69018-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References

Wan, Maisonneuve, Szilard, Lambert, Ng, Manczyk, Huang, Laister, Caudy, Gingras, Durocher, Sicheri: "Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7." in: Nucleic acids research, Vol. 45, Issue 2, pp. 805-817, (2016) (PubMed).

Target Details

Target: GON7 Subunit Of KEOPS Complex (GON7)

Alternative Name: GON7

Background:

Gene Name: GON7, KEOPS complex subunit

Alternative Symbols: PNAS-127, C14orf142

Protein Name: EKC/KEOPS complex subunit GON7

Molecular Weight: 11kDa

Gene ID: 84520

NCBI Accession: NP_115879

UniProt: Q9BXV9