HIST1H4A antibody (N-Term)

Catalog No. ABIN2774551

Product Details anti-HIST1H4A Antibody

Target: HIST1H4A (Histone Cluster 1, H4a (HIST1H4A))

Binding Specificity: N-Term

Reactivity: Mouse, Rat, Cow, Zebrafish (Danio rerio), Goat, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H4A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL IYEETRGVLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against HIST1H4A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HIST1H4A

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIST1H4A

Target: HIST1H4A (Histone Cluster 1, H4a (HIST1H4A))

Alternative Name: HIST1H4A (HIST1H4A Products)

Synonyms: Hist1h4a antibody, H4FA antibody, histone cluster 1, H3f antibody, histone cluster 1 H4 family member a antibody, histone cluster 1, H4a antibody, Hist1h3f antibody, HIST1H4A antibody, Hist1h4a antibody

Background: HIST1H4A is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Alias Symbols: H4/p
Protein Interaction Partner: UBC, DTX3L, RBBP4, H3F3A, CENPA, HIST1H3A, HDAC2, ASB9, ASB16, L3MBTL2, rev, ARFIP1, JMJD6, XPO7, FAF1, HSPH1, SEC23A, PRMT3, RBX1, HIRIP3, CUL1, ZYX, SF1, TTC1, TROVE2, SHMT1, RPL24, PPM1G, OSBP, GFPT1, GARS, CARS, FBXO6, PAN2, PRMT8, RL1, HCVgp1, ITGA4,
Protein Size: 103

Molecular Weight: 11 kDa

Gene ID: 8359

NCBI Accession: NM_175054, NP_778224

UniProt: P62805