HIST1H4A antibody (N-Term)

Catalog No. ABIN2774551

The Rabbit Polyclonal anti-HIST1H4A antibody (ABIN2774551) specifically detects HIST1H4A in WB. The antibody is reactive with Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Goat and Guinea Pig samples.

Quick Overview for HIST1H4A antibody (N-Term) (ABIN2774551)

Target: HIST1H4A (Histone Cluster 1, H4a (HIST1H4A))

Reactivity: Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Goat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H4A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIST1H4A Antibody

Binding Specificity: N-Term

Purpose: HIST1H4A Antibody - N-terminal region

Sequence: LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL IYEETRGVLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against HIST1H4A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HIST1H4A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP70540-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIST1H4A

Target: HIST1H4A (Histone Cluster 1, H4a (HIST1H4A))

Alternative Name: HIST1H4A

Background:

Background Information: HIST1H4A is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Alternative Symbols: H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4FA, H4-16, H4C11, H4C12, H4C13, H4C14, H4C15, HIST1H4A

Protein Name: Histone H4

Molecular Weight: 11kDa

Gene ID: 8359

NCBI Accession: NP_778224

UniProt: P62805