c-Rel antibody (N-Term)
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- Target See all c-Rel Antibodies
- c-Rel (REL proto-oncogene (c-Rel))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This c-Rel antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ASGAYNPYIE IIEQPRQRGM RFRYKCEGRS AGSIPGEHST DNNRTYPSIQ
- Cross-Reactivity
- Chicken, Human, Mouse (Murine)
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Zebrafish: 85%
- Characteristics
- This is a rabbit polyclonal antibody against REL. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human REL
- Top Product
- Discover our top product c-Rel Primary Antibody
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- Application Notes
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WB Suggested Anti-REL Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: Hela cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Comment
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Antigen size: 619 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- c-Rel (REL proto-oncogene (c-Rel))
- Alternative Name
- REL (c-Rel Products)
- Synonyms
- C-Rel antibody, c-Rel antibody, NFkB antibody, c-rel antibody, zgc:100833 antibody, Xrel2 antibody, Xrel3 antibody, rel antibody, rel-A antibody, rel2 antibody, rel3 antibody, v-rel antibody, xrel antibody, REL proto-oncogene, NF-kB subunit antibody, reticuloendotheliosis oncogene antibody, RELA proto-oncogene, NF-kB subunit antibody, v-rel avian reticuloendotheliosis viral oncogene homolog antibody, v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog antibody, ribonuclease A family member 2 pseudogene antibody, REL antibody, Rel antibody, Rela antibody, rel antibody, rel.L antibody, ECRP antibody
- Background
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REL is a member of the Rel/NFKB family, which also includes RELA, RELB, NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor.The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-174 CN414487.1 2-175 175-2323 X75042.1 128-2276 2324-2457 BX111941.1 575-708 2458-2592 AA279919.1 1-135 c
Alias Symbols: C-Rel
Protein Interaction Partner: NFKB2, REXO1L6P, C12orf75, TRIM74, RAB41, BARHL2, SEC14L4, NUDT14, ZDHHC24, NEIL2, CPNE2, C9orf72, STRA13, TTC21A, FUT11, ZNF564, ZNF550, PATE1, TSTD2, ZNF417, ZNF572, GLYCTK, EGLN3, RIPPLY1, ZNF765, ATPAF2, SLC39A13, BMF, KRTAP9-4, CEP19, VPS25, MIEN1, P
Protein Size: 619 - Molecular Weight
- 68 kDa
- Gene ID
- 5966
- NCBI Accession
- NM_002908, NP_002899
- UniProt
- Q04864
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