FBXL3 antibody (C-Term)
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- Target See all FBXL3 Antibodies
- FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FBXL3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ELLLALSSEK HVRLEHLRID VVSENPGQTH FHTIQKSSWD AFIKHSPKVN
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against Fbxl3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product FBXL3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 428 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))
- Alternative Name
- Fbxl3 (FBXL3 Products)
- Background
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Fbxl3 is a substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
Alias Symbols: AU041772, AW212966, FBK, Fbl3a, Fbxl3a, Ovtm
Protein Interaction Partner: Skp1a, Cry2, Cry1,
Protein Size: 428 - Molecular Weight
- 49 kDa
- Gene ID
- 50789
- NCBI Accession
- NM_015822, NP_056637
- UniProt
- Q8C4V4
- Pathways
- Photoperiodism
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