FBXO25 antibody (C-Term)

Catalog No. ABIN2774696

This Rabbit Polyclonal antibody specifically detects FBXO25 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Horse, Guinea Pig, Cow and Rabbit.

Quick Overview for FBXO25 antibody (C-Term) (ABIN2774696)

Target: FBXO25 (F-Box Protein 25 (FBXO25))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Horse, Guinea Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO25 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FBXO25 Antibody

Binding Specificity: C-Term

Sequence: AKEQYGDTLH FCRHCSILFW KDSGHPCTAA DPDSCFTPVS PQHFIDLFKF

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO25. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FBXO25

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 141 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO25

Target: FBXO25 (F-Box Protein 25 (FBXO25))

Alternative Name: FBXO25

Background: FBXO25 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO25 belongs to the Fbxs class.
Alias Symbols: FBX25, MGC20256, MGC51975
Protein Interaction Partner: SYTL2, ING3, TMA7, HP1BP3, ADRBK1, PRRG1, PRKG2, PRKCA, PPP1R8, PPID, PDGFRA, PCK1, ODF2, KRT8, KDR, IRS1, DNAJB2, HIP1, GTF2B, FKBP3, ELK1, EGFR, DCX, EID3, PRR15, APLF, TCEANC, WDSUB1, TRUB1, TCEAL2, TCP10L, ANKRD13A, C7orf50, RHBDD1, NSRP1, RABEP2, C11
Protein Size: 141

Molecular Weight: 16 kDa

Gene ID: 26260

NCBI Accession: NM_012173

UniProt: Q8TCJ0