FBXO7 antibody (Middle Region)

Catalog No. ABIN2774701

Product Details anti-FBXO7 Antibody

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO7 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Sequence: PGETPSQFPP LRPRFDPVGP LPGPNPILPG RGGPNDRFPF RPSRGRPTDG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against FBXO7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 522 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO7

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Alternative Name: FBXO7 (FBXO7 Products)

Synonyms: fbxo7 antibody, MGC80085 antibody, FBXO7 antibody, fbx7 antibody, MGC135804 antibody, MGC145325 antibody, ATFBP7 antibody, F-BOX PROTEIN 7 antibody, F-box protein 7 antibody, F8K7.20 antibody, F8K7_20 antibody, DKFZp469H0739 antibody, si:ch211-286m4.2 antibody, zgc:114096 antibody, FBX antibody, FBX07 antibody, FBX7 antibody, PARK15 antibody, PKPS antibody, 2410015K21Rik antibody, A230052G17Rik antibody, AI117679 antibody, AW260462 antibody, C85118 antibody, F-box protein 7 antibody, F-box protein 7 L homeolog antibody, FBXO7 antibody, fbxo7.L antibody, fbxo7 antibody, FBP7 antibody, Fbxo7 antibody

Background: FBXO7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO7 belongs to the Fbxs class and it may play a role in regulation of hematopoiesis.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
Alias Symbols: DKFZp686B08113, FBX, FBX07, FBX7, PKPS, PARK15
Protein Interaction Partner: PSME3, PSMF1, PSMA3, SKP1, TRAF2, MAGED1, SHFM1, PINK1, PARK2, SEC24C, NEDD8, UBC, COPS5, COPS6, CUL1, BIRC2, RBBP6, XPO1, DLGAP5, ELF4, BIRC3, CDK6, UBE2D2, CDC34,
Protein Size: 522

Molecular Weight: 58 kDa

Gene ID: 25793

NCBI Accession: NM_012179, NP_036311

UniProt: Q9Y3I1