UBE2J1 antibody (N-Term)
Quick Overview for UBE2J1 antibody (N-Term) (ABIN2774737)
Target
See all UBE2J1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- METRYNLKSP AVKRLMKEAA ELKDPTDHYH AQPLEDNLFE WHFTVRGPPD
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Predicted Reactivity
- Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Characteristics
- This is a rabbit polyclonal antibody against UBE2J1. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2J1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 318 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UBE2J1 (Ubiquitin-Conjugating Enzyme E2, J1, U (UBE2J1))
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Alternative Name
- UBE2J1
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Background
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2J1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.
Alias Symbols: CGI-76, HSPC153, HSPC205, HSU93243, MGC12555, NCUBE1, Ubc6p, UBC6, NCUBE-1
Protein Interaction Partner: UBC, UBA1, MAPKAPK2, OS9, RNF5, PARK2, DIO2, SOX6, TP53, AUP1, ASNA1, DERL3, DERL1, YOD1, DERL2, FAF2, VCP, SEL1L, ELAVL1, HLA-A, BIRC2, LRSAM1, TRIM63, SYVN1, TOPORS, PJA2, RNF2, TRIM27, BRCA1, BIRC3,
Protein Size: 318 -
Molecular Weight
- 35 kDa
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Gene ID
- 51465
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NCBI Accession
- NM_016021, NP_057105
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UniProt
- Q9Y385
Target
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