FBXO11 antibody (Middle Region)

Catalog No. ABIN2774788

This anti-FBXO11 antibody is a Rabbit Polyclonal antibody detecting FBXO11 in WB and ChIP. Suitable for Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Dog, Guinea Pig and Rabbit.

Quick Overview for FBXO11 antibody (Middle Region) (ABIN2774788)

Target: FBXO11 (F-Box Protein 11 (FBXO11))

Reactivity: Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO11 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Product Details anti-FBXO11 Antibody

Binding Specificity: Middle Region

Sequence: HDVEFIRHDR FFCDCGAGTL SNPCTLAGEP THDTDTLYDS APPIESNTLQ

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 843 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO11

Target: FBXO11 (F-Box Protein 11 (FBXO11))

Alternative Name: FBXO11

Background: FBXO11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for FBXO11.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: FBX11, FLJ12673, MGC44383, PRMT9, UG063H01, VIT1, UBR6
Protein Interaction Partner: SKP1, ERN1, DTL, CUL1, EED, UBC, NEDD8, COPS5, COPS6, ELAVL1, USP16, HDAC6, BCL6, RBX1, TP53,
Protein Size: 843

Molecular Weight: 94 kDa

Gene ID: 80204

NCBI Accession: NM_025133, NP_079409

UniProt: Q6DF73

Pathways: Sensory Perception of Sound