RUFY1 antibody (C-Term)

Catalog No. ABIN2774789

This Rabbit Polyclonal antibody specifically detects RUFY1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio) and Horse.It has been mentioned in 1 publication

Quick Overview for RUFY1 antibody (C-Term) (ABIN2774789)

Target: RUFY1 (RUN and FYVE Domain Containing 1 (RUFY1))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUFY1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RUFY1 Antibody

Binding Specificity: C-Term

Purpose: RUFY1 Antibody - C-terminal region

Sequence: QCEKEFSISR RKHHCRNCGH IFCNTCSSNE LALPSYPKPV RVCDSCHTLL

Predicted Reactivity: Cow: 85%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RUFY1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RUFY1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43329-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-RUFY1 antibody (ABIN2774789)

Suzuki, Fujisawa, Ando, Niino, Ohsawa, Shimokata, Ohta: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).

Target Details for RUFY1

Target: RUFY1 (RUN and FYVE Domain Containing 1 (RUFY1))

Alternative Name: RUFY1

Background:

Background Information: RUFY1 contains 1 FYVE-type zinc finger and 1 RUN domain. It binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.

Gene Name: RUN and FYVE domain containing 1

Alternative Symbols: RABIP4, ZFYVE12

Protein Name: cDNA FLJ78384, highly similar to Homo sapiens RUN and FYVE domain containing 1 (RUFY1), mRNA EMBL BAF84615.1

Molecular Weight: 69kDa

Gene ID: 80230

NCBI Accession: NP_001035542

UniProt: A8K7B1