ANXA6 antibody (C-Term)

Catalog No. ABIN2774841

This Rabbit Polyclonal antibody specifically detects ANXA6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig and Rabbit.

Quick Overview for ANXA6 antibody (C-Term) (ABIN2774841)

Target: ANXA6 (Annexin A6 (ANXA6))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANXA6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ANXA6 Antibody

Binding Specificity: C-Term

Purpose: Anxa6 Antibody - C-terminal region

Sequence: SDTSGHFRRI LISLATGHRE EGGENLDQAR EDAQVAAEIL EIADTPSGDK

Predicted Reactivity: Guinea Pig: 79%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ANXA6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human Anxa6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094737

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ANXA6

Target: ANXA6 (Annexin A6 (ANXA6))

Alternative Name: Anxa6

Background:

Background Information: Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.

Gene Name: Annexin A6

Alternative Symbols: p68, p70, ANX6, CBP68, CPB-II

Protein Name: Annexin A6

Molecular Weight: 74kDa

Gene ID: 309

NCBI Accession: NP_001146

UniProt: P08133