GJA8 antibody (Middle Region)

Catalog No. ABIN2774860

The Rabbit Polyclonal anti-GJA8 antibody has been validated for WB. It is suitable to detect GJA8 in samples from Human, Mouse, Rat, Dog and Horse.

Quick Overview for GJA8 antibody (Middle Region) (ABIN2774860)

Target: GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

Reactivity: Human, Mouse, Rat, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJA8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GJA8 Antibody

Binding Specificity: Middle Region

Sequence: EEQEKVAVPE GEKVETPGVD KEGEKEEPQS EKVSKQGLPA EKTPSLCPEL

Predicted Reactivity: Dog: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against GJA8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GJA8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 433 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GJA8

Target: GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

Alternative Name: GJA8

Background: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1).
Alias Symbols: CAE, CAE1, CX50, CZP1, MP70
Protein Interaction Partner: TJP1, MIP,
Protein Size: 433

Molecular Weight: 48 kDa

Gene ID: 2703

NCBI Accession: NM_005267, NP_005258

UniProt: P48165