GJA3 antibody (N-Term)

Catalog No. ABIN2774868

This Rabbit Polyclonal antibody specifically detects GJA3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Horse, Pig and Saccharomyces cerevisiae.

Quick Overview for GJA3 antibody (N-Term) (ABIN2774868)

Target: GJA3 (Gap Junction Protein, alpha 3, 46kDa (GJA3))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Horse, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJA3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GJA3 Antibody

Binding Specificity: N-Term

Sequence: ISHIRFWALQ IIFVSTPTLI YLGHVLHIVR MEEKKKEREE EEQLKRESPS

Predicted Reactivity: Horse: 91%, Human: 100%, Mouse: 83%, Pig: 91%, Rat: 90%, Yeast: 91%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against GJA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GJA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 435 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GJA3

Target: GJA3 (Gap Junction Protein, alpha 3, 46kDa (GJA3))

Alternative Name: GJA3

Background: GJA3 belongs to the connexin family. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3).
Alias Symbols: CX46, CZP3
Protein Interaction Partner: UBC, CAV1, TJP1, PRKCG, MIP, GJA1,
Protein Size: 435

Molecular Weight: 47 kDa

Gene ID: 2700

NCBI Accession: NM_021954, NP_068773

UniProt: Q9Y6H8