TJP1 antibody (Middle Region)
Quick Overview for TJP1 antibody (Middle Region) (ABIN2774876)
Target
See all TJP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- QNHVLKQPAV SHPGHRPDKE PNLTYEPQLP YVEKQASRDL EQPTYRYESS
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Predicted Reactivity
- Dog: 92%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 87%, Pig: 93%, Rabbit: 100%, Rat: 93%
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Characteristics
- This is a rabbit polyclonal antibody against TJP1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TJP1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 1668 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TJP1 (Tight Junction Protein 1 (TJP1))
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Alternative Name
- TJP1
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Background
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TJP1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. TJP1 may be involved in signal transduction at cell-cell junctions.This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: DKFZp686M05161, MGC133289, ZO-1
Protein Interaction Partner: VMP1, RAPGEF2, LATS2, TJP2, PAN2, DTNA, UBC, SCO2, VAPA, VAPB, ZPR1, NOTCH2, NDUFV2, NDUFS6, SUGP1, RTN4, STRN, PARD3, PARD6A, PRKCI, SIRT7, KHDRBS1, ELAVL1, SSTR3, Cdk1, TUBA1C, TUBB4A, VIM, SPTAN1, PLEC, KRT10, KRT8, KRT1, GJA1, FLNA, ANXA6, ACTN1, ACTN
Protein Size: 1668 -
Molecular Weight
- 187 kDa
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Gene ID
- 7082
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NCBI Accession
- NM_175610, NP_783297
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UniProt
- Q07157
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Pathways
- Carbohydrate Homeostasis, Cell-Cell Junction Organization
Target
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