TJP1 antibody (Middle Region)

Catalog No. ABIN501576

The Rabbit Polyclonal anti-TJP1 antibody (ABIN501576) specifically detects TJP1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Pig, Dog, Guinea Pig, Rabbit and Horse samples.

Quick Overview for TJP1 antibody (Middle Region) (ABIN501576)

Target: TJP1 (Tight Junction Protein 1 (TJP1))

Reactivity: Human, Mouse, Rat, Pig, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TJP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TJP1 Antibody

Binding Specificity: Middle Region

Sequence: QNHVLKQPAV SHPGHRPDKE PNLTYEPQLP YVEKQASRDL EQPTYRYESS

Predicted Reactivity: Dog: 92%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 87%, Pig: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TJP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TJP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1668 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TJP1

Target: TJP1 (Tight Junction Protein 1 (TJP1))

Alternative Name: TJP1

Background: TJP1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. TJP1 may be involved in signal transduction at cell-cell junctions.This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: DKFZp686M05161, MGC133289, ZO-1
Protein Interaction Partner: VMP1, RAPGEF2, LATS2, TJP2, PAN2, DTNA, UBC, SCO2, VAPA, VAPB, ZPR1, NOTCH2, NDUFV2, NDUFS6, SUGP1, RTN4, STRN, PARD3, PARD6A, PRKCI, SIRT7, KHDRBS1, ELAVL1, SSTR3, Cdk1, TUBA1C, TUBB4A, VIM, SPTAN1, PLEC, KRT10, KRT8, KRT1, GJA1, FLNA, ANXA6, ACTN1, ACTN
Protein Size: 1668

Molecular Weight: 187 kDa

Gene ID: 7082

NCBI Accession: NM_175610, NP_783297

UniProt: Q07157

Pathways: Carbohydrate Homeostasis, Cell-Cell Junction Organization