Annexin V antibody (N-Term)

Catalog No. ABIN2774910

Product Details anti-Annexin V Antibody

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Pig, Dog, Sheep, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin V antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AYELKHALKG AGTNEKVLTE IIASRTPEEL RAIKQVYEEE YGSSLEDDVV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against ANXA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 320 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Annexin V

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Alternative Name: ANXA5 (ANXA5 Products)

Synonyms: anx antibody, anx5 antibody, ANX V antibody, anxa5 antibody, cb989 antibody, wu:fa98f06 antibody, wu:fj10f10 antibody, MGC89158 antibody, ANX5 antibody, ENX2 antibody, PP4 antibody, RPRGL3 antibody, Anx5 antibody, R74653 antibody, LC5 antibody, enx2 antibody, annexin A5 antibody, annexin A5b antibody, Annexin A5 antibody, annexin A5 L homeolog antibody, ANXA5 antibody, anxa5b antibody, anxa5 antibody, Anxa5 antibody, anxa5.L antibody

Background: ANXA5 belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
Alias Symbols: PP4, ANX5, ENX2, RPRGL3
Protein Interaction Partner: HUWE1, UBC, FUS, TUBGCP3, ASB9, BAG3, LAMC3, ATF2, VCP, NDRG1, PUM1, PPT2, HARS, APP, CDK2, TERF2IP, TINF2, ISG15, TERF2, TERF1, ANXA1, SUMO2, SUMO1, AI837181, Pds5a, PPP2R1B, H2AFX, SUPT4H1, EED, EIF4G1, KDR, FDFT1, IFNGR2, ITGB5, COL2A1, COL10A1, ACTG1,
Protein Size: 320

Molecular Weight: 35 kDa

Gene ID: 308

NCBI Accession: NM_001154, NP_001145

UniProt: Q6FHB3

Pathways: Apoptosis