Annexin V antibody (N-Term)

Catalog No. ABIN2774910

The Rabbit Polyclonal anti-Annexin V antibody (ABIN2774910) specifically detects Annexin V in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Rabbit, Pig, Dog, Sheep, Horse and Guinea Pig samples.

Quick Overview for Annexin V antibody (N-Term) (ABIN2774910)

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Pig, Dog, Sheep, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin V antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Annexin V Antibody

Binding Specificity: N-Term

Purpose: ANXA5 Antibody - N-terminal region

Sequence: AYELKHALKG AGTNEKVLTE IIASRTPEEL RAIKQVYEEE YGSSLEDDVV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against ANXA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36687-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Annexin V

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Alternative Name: ANXA5

Background:

Background Information: ANXA5 belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.

Gene Name: Annexin A5

Alternative Symbols: PP4, ANX5, ENX2, RPRGL3, HEL-S-7

Protein Name: Annexin A5

Molecular Weight: 35kDa

Gene ID: 308

NCBI Accession: NP_001145

UniProt: Q6FHB3

Pathways: Apoptosis