SSX5 antibody (Middle Region)

Catalog No. ABIN2774973

The Rabbit Polyclonal anti-SSX5 antibody (ABIN2774973) specifically detects SSX5 in WB. The antibody is reactive with Human samples.

Quick Overview for SSX5 antibody (Middle Region) (ABIN2774973)

Target: SSX5 (Synovial Sarcoma, X Breakpoint 5 (SSX5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSX5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SSX5 Antibody

Binding Specificity: Middle Region

Purpose: SSX5 Antibody - middle region

Sequence: GRLQGIFPKI TPEKPAEEGN DSKGVPEASG PQNNGKQLRP SGKLNTSEKV

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SSX5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SSX5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35989-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SSX5

Target: SSX5 (Synovial Sarcoma, X Breakpoint 5 (SSX5))

Alternative Name: SSX5

Background:

Background Information: SSX5 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. The gene encoding SSX5 appears not to be involved in this type of chromosome translocation. The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: Synovial sarcoma, X breakpoint 5

Alternative Symbols: MGC9494

Protein Name: Protein SSX5

Molecular Weight: 26kDa

Gene ID: 6758

NCBI Accession: NP_066295

UniProt: Q5JQ60