CRX antibody (N-Term)

Catalog No. ABIN2775168

Product Details anti-CRX Antibody

Target: CRX (Cone-Rod Homeobox (CRX))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRX antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VDLMHQAVPY PSPPLALDPP RRQRQERTVY TESQQKVLEF YFQKDQYPNY

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CRX. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human CRX

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRX

Target: CRX (Cone-Rod Homeobox (CRX))

Alternative Name: CRX (CRX Products)

Synonyms: Xotx5 antibody, Xotx5b antibody, cord2 antibody, crd antibody, otx5 antibody, otx5b antibody, rx antibody, CRX antibody, crx antibody, otx5-b antibody, CORD2 antibody, CRD antibody, LCA7 antibody, OTX3 antibody, Crx1 antibody, otx5-A antibody, cone-rod homeobox antibody, cone-rod homeobox L homeolog antibody, cone-rod homeobox S homeolog antibody, crx antibody, CRX antibody, Crx antibody, crx.L antibody, crx.S antibody

Background: The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Alias Symbols: CRD, LCA7, OTX3, CORD2
Protein Size: 326

Molecular Weight: 35 kDa

Gene ID: 1406

NCBI Accession: NM_000554, NP_000545

UniProt: O43186