CRX antibody (N-Term)

Catalog No. ABIN2775168

The Rabbit Polyclonal anti-CRX antibody is suitable to detect CRX in samples from Human. It has been validated for WB.

Quick Overview for CRX antibody (N-Term) (ABIN2775168)

Target: CRX (Cone-Rod Homeobox (CRX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRX Antibody

Binding Specificity: N-Term

Purpose: CRX Antibody - N-terminal region

Sequence: VDLMHQAVPY PSPPLALDPP RRQRQERTVY TESQQKVLEF YFQKDQYPNY

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CRX. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human CRX

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36301-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRX

Target: CRX (Cone-Rod Homeobox (CRX))

Alternative Name: CRX

Background:

Background Information: The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

Gene Name: cone-rod homeobox

Alternative Symbols: CRD, LCA7, OTX3, CORD2

Protein Name: cone-rod homeobox protein

Molecular Weight: 35kDa

Gene ID: 1406

NCBI Accession: NP_000545

UniProt: O43186