AKAP7 antibody (N-Term)

Catalog No. ABIN2775178

The Rabbit Polyclonal anti-AKAP7 antibody is suitable to detect AKAP7 in samples from Human. It has been validated for WB and IHC.

Quick Overview for AKAP7 antibody (N-Term) (ABIN2775178)

Target: AKAP7 (A Kinase (PRKA) Anchor Protein 7 (AKAP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-AKAP7 Antibody

Binding Specificity: N-Term

Purpose: AKAP7 Antibody - N-terminal region

Sequence: MGQLCCFPFS RDEGKISELE SSSSAVLQRY SKDIPSWSSG EKNGGEPDDA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against AKAP7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AKAP7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8093717

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AKAP7

Target: AKAP7 (A Kinase (PRKA) Anchor Protein 7 (AKAP7))

Alternative Name: AKAP7

Background:

Background Information: AKAP7 is a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.

Gene Name: A kinase (PRKA) anchor protein 7

Alternative Symbols: AKAP15, AKAP18

Protein Name: A-kinase anchor protein 7 isoforms alpha and beta

Molecular Weight: 11kDa

Gene ID: 9465

NCBI Accession: NP_619539

UniProt: O43687