DHX38 antibody (Middle Region)

Catalog No. ABIN2775220

The Rabbit Polyclonal anti-DHX38 antibody (ABIN2775220) specifically detects DHX38 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for DHX38 antibody (Middle Region) (ABIN2775220)

Target: DHX38 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 38 (DHX38))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX38 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DHX38 Antibody

Binding Specificity: Middle Region

Purpose: DHX38 Antibody - middle region

Sequence: HKHWELAGTK LGDIMGVKKE EEPDKAVTED GKVDYRTEQK FADHMKRKSE

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against DHX38. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36412-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DHX38

Target: DHX38 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 38 (DHX38))

Alternative Name: DHX38

Background:

Background Information: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process.

Gene Name: DEAH (Asp-Glu-Ala-His) box polypeptide 38

Alternative Symbols: RP84, DDX38, PRP16, PRPF16

Protein Name: Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

Molecular Weight: 140kDa

Gene ID: 9785

NCBI Accession: NP_054722

UniProt: Q92620