DHX38 antibody (Middle Region)

Catalog No. ABIN2775220

Product Details anti-DHX38 Antibody

Target: DHX38 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 38 (DHX38))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX38 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HKHWELAGTK LGDIMGVKKE EEPDKAVTED GKVDYRTEQK FADHMKRKSE

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against DHX38. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1227 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DHX38

Target: DHX38 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 38 (DHX38))

Alternative Name: DHX38 (DHX38 Products)

Synonyms: zgc:63517 antibody, DHX38 antibody, DDX38 antibody, PRP16 antibody, PRPF16 antibody, 5730550P09Rik antibody, AI325984 antibody, AW540902 antibody, Ddx38 antibody, Prp16 antibody, mKIAA0224 antibody, DEAH (Asp-Glu-Ala-His) box polypeptide 38 antibody, DEAH-box helicase 38 antibody, pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 antibody, dhx38 antibody, DHX38 antibody, LOC100638345 antibody, Dhx38 antibody

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process.
Alias Symbols: DDX38, KIAA0224, PRP16, PRPF16
Protein Interaction Partner: SUMO2, NUDCD1, UBC, ASB12, PSMB8, COPA, GPKOW, DHX16, RBM10, U2AF1, MFAP1, CSNK2A1, LSM2, SNW1, SLU7, CWC27, RBM8A, DDX39B, RPS20, RBBP5, PRKDC, DDX5, UBD, CUL3, TERF2IP, SIRT7, Prpf8, USP39, CDC40, PPP4C, RNPS1,
Protein Size: 1227

Molecular Weight: 140 kDa

Gene ID: 9785

NCBI Accession: NM_014003, NP_054722

UniProt: Q92620