DDX58 antibody (Middle Region)

Catalog No. ABIN2775222

Product Details anti-DDX58 Antibody

Target: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Binding Specificity: Middle Region

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX58 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EECHYTVLGD AFKECFVSRP HPKPKQFSSF EKRAKIFCAR QNCSHDWGIH

Predicted Reactivity: Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against DDX58. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DDX58

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 925 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DDX58

Target: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Alternative Name: DDX58 (DDX58 Products)

Synonyms: RIG-I antibody, RIGI antibody, RLR-1 antibody, 6430573D20Rik antibody, C330021E21 antibody, RHIV-1 antibody, RIG-1 antibody, DExD/H-box helicase 58 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 antibody, DEXD/H-box helicase 58 antibody, DDX58 antibody, Ddx58 antibody

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein
Alias Symbols: DKFZp434J1111, DKFZp686N19181, FLJ13599, RIG-I
Protein Interaction Partner: MAVS, TRIM25, RNF135, TRIM26, UBC, MEX3C, USP21, USP3, TBK1, IKBKE, IKBKG, Casp12, NLRC5, DDX58, USP4, MBP, IRF3, SRC, TSPAN6, TRIM32, ISG15, PRKCG, PRKCB, PRKCA, WRNIP1, RNF31, RAI14, RBCK1, PRKRIR, UBE2D3, UBE2D2, UBE2D1, UBE2K, CYLD,
Protein Size: 925

Molecular Weight: 106 kDa

Gene ID: 23586

NCBI Accession: NM_014314, NP_055129

UniProt: O95786

Pathways: Activation of Innate immune Response, Hepatitis C